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Administrarea Imovane impreuna cu buprenorfina sau cu medicamente barbiturice creste riscul de deprimare respiratorie, treatment poate avea efect letal. Należy wówczas stosować najmniejszą skuteczną dawkę przez możliwie najkrótszy czas i zachować zalecone środki ostrożności. Należy obserwować chorego czy nie występują u niego
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